Bioreactor suite

a monoclonal antibody fermentation suite running isa 88 batches media charge, bioreactor, harvest, with the cleanroom environment judged across the whole batch five devices and 94 tags over modbus tcp operator view on 4011 , modbus tcp on 5021 what it demonstrates a batch that cannot be released a critical process parameter leaves its recipe band for long enough to matter the deviation is recorded against the batch, not against a shift, and it is visible while the batch is still running right first time across a campaign, the proportion of batches that completed without a deviation, which is the number a quality organisation is actually measured on the batch record itself an electronic record assembled from what litmus edge recorded phases, parameters, deviations and environment, exportable at the end of the batch what it puts on litmus edge five devicehub devices covering the reactor, the media charge and harvest vessels, the temperature control unit and the cleanroom, with 94 tags a digital twin model and instance per vessel analytics groups behind the deviation, yield and release figures deploy services pharma bioreactor image us docker pkg dev/litmus customer facing/litmus solutions/pharma bioreactor demo 0 1 0 container name pharma bioreactor demo restart unless stopped ports \ target 4011 published 4011 protocol tcp \ target 5021 published 5021 protocol tcp environment \# fill these in edge url "${edge url }" edge api token "${edge api token }" sim host "${sim host auto}" apply on start "${apply on start 1}" edge verify tls "${edge verify tls 0}" http port "4011" modbus port "5021" autostart "1" tick seconds "0 2" seed "11" log level "info" edge url=https //10 0 0 5 edge api token=your token sim host=10 0 0 9 docker compose up d open http //localhost 4011 configuration variable default what it does edge url the docker host litmus edge to configure edge api token unset token for that edge or a username and password, or a client id and secret sim host auto address the edge polls to reach this solution apply on start 1 configure the edge on startup edge verify tls 0 1 checks the edge's certificate autostart 1 start a batch on boot seed 11 makes a run repeatable what you see the batch runs through its isa 88 phases along the top sterilise in place, charge media, growth, harvest below, the vessels fill and drain, the agitator turns, and each critical process parameter is shown against the recipe band it has to stay inside the environment section is judged across the whole batch rather than sampled, so a room pressure excursion during growth counts against the batch even if the reading has recovered by harvest preview or export the batch record at any point to see what has been recorded so far faults available include parameter excursions, a jacket temperature fault and a cleanroom pressure loss removing it docker compose down use clean up in the solutions provisioner # to remove what it created on the edge support support\@litmus io mailto\ support\@litmus io